Dizziness, headache, anemia, more problems? Doctor: Do a blood test to prevent myeloproliferative tumor!

Feeling dizzy, headache, anemia, fatigue, insomnia, etc., many problems are quite common in daily life. People usually do a check, but sometimes they can’t find the cause, or even there is no anemia at all, but the problem remains.

The Taiwan Myeloproliferative Tumor Care Association established a press conference to appeal that if you encounter such a situation, it is recommended to pay more attention to the blood drawing report or do a blood test, and be careful of “myeloproliferative tumors” to prevent major diseases such as stroke and myocardial infarction. .

What’s wrong with anemia? Ageing?
Doctor: Also pay attention to myeloproliferative tumors!

Myeloproliferative neoplasm is a rare disease, due to the gene mutation of bone marrow hematopoietic stem cells, leading to uncontrolled abnormal proliferation of bone marrow hematopoiesis. It can happen to the elderly or the young.

Physician Chen Zhicheng, director of the Myeloproliferative Tumor Treatment and Research Center of Chiayi Chang Gung Hospital, pointed out that the symptoms of this disease may include fatigue, night sweats, itching, fever, weight loss, tinnitus, headache, insomnia, etc., and may also be accompanied by an enlarged spleen, which may further compress the stomach and intestines. Discomfort such as bloating, loss of appetite, etc.

In addition, due to abnormal hematopoietic hyperplasia, the blood is too thick, and it is easy to have problems related to blood circulation disorders, such as dizziness, blurred vision, numbness in hands and feet, etc., and even complications such as bleeding and thrombosis. , or the occurrence of major hazards such as stroke, myocardial infarction, and pulmonary embolism.

According to the literature, even in advanced western countries, it takes an average of about 2 years from the onset of symptoms to the diagnosis of the disease, and more than 60% of them are diagnosed because of stroke or pulmonary embolism. “Sometimes I look up the patient’s report 2 or 3 years ago and find that the patient has long been abnormal, but he has not actively sought medical treatment, and he does not know how to prevent it.”

Dizziness, headache, anemia, more problems?
Doctor: Take a blood to prevent myeloproliferative tumor!

Since the symptoms of myeloproliferative neoplasms are so similar to common daily problems and difficult to detect, and this disease is rare and dangerous, how should the public take appropriate precautions?

In this regard, Hou Xinan, chairman of the Taiwan Myeloproliferative Tumor Care Association, suggested that if people have symptoms related to myeloproliferative tumors on a daily basis, but they are not sure if it is, or they cannot find other reasons, they can have a blood draw if they have any doubts. Check, the general blood test report can see whether it is normal, so as to know whether there is a myeloproliferative tumor.

Chairman Hou Xinan took true erythroid hyperplasia as an example. For males, the red blood cell ratio is greater than 16.5g/dl or the hematocrit is less than 49%. In addition, further examinations can be carried out through bone marrow biopsy, genetic testing, etc.

For the treatment of myeloproliferative tumors, the
new drug starts to be paid by health insurance on 9/1!

The treatment of myeloproliferative tumors will depend on the type and risk. Chairman Hou Xinan took erythrocytosis vera as an example, and low-risk groups such as bloodletting therapy and low-dose aspirin. Bloodletting is actually like donating blood, releasing red blood cells to lower the hematocrit, the expected value is below 45%. Low-dose aspirin can prevent blood clots. In addition to the above two types of treatment for high-risk groups, oral chemotherapy drugs or long-acting interferon therapy are usually used in combination, all of which are covered by health insurance.

In recent years, the US FDA, EU EMA, and Taiwan and other countries have also approved “new long-acting interferon”, which can be used for the treatment of erythrocytosis vera. Taiwan’s Health Insurance Administration also approved health insurance on 9/1, providing health insurance benefits for some high-risk groups and those with poor traditional treatment. The new long-acting interferon health insurance benefits conditions, including:

1. Restricted to high-risk groups.

2. Use phlebotomy at least once every 3 months or more, and at least 4 times a year. And those who have received cytoreduction therapy to the maximum allowable dose, but still cannot reach the blood volume ratio below 45%, or have serious side effects of CTCAE2.0 Grade 3 or above.

The woman was dizzy and tired, and the blood was abnormal, and the
examination confirmed myeloproliferative tumor!

At the press conference, Mrs. Huang, a patient in her 80s, was also invited to share her experience. Before the diagnosis, he became easily tired, dizzy from time to time, the world was spinning, and he was easily dizzy and nauseous, but the same was true for 9 out of 10 friends around him.

In order to find out the reason, the daughter also took her for a general blood test, but the clinic called her home to apologize, saying that the sample was suspected to be not well preserved and contaminated, and the blood report was abnormal. However, after the second examination was the same as abnormal, the doctor determined that it was not the contamination of the blood sample, but the data was indeed abnormal, and the diagnosis was myeloproliferative tumor after referral to the medical center.

I simply searched the Internet for information on my daughter, and found that there were also new drugs for myeloproliferative tumors to be marketed in China at that time, so I began to receive new long-acting interferon therapy in July 2020, otherwise I planned to fly to Europe for treatment. After two years of treatment, Mrs. Huang’s daily activities are now completely unaffected by the disease, and she still has few problems such as taking a walk in the park in the morning, occasionally participating in club activities, and dizziness.

Prevent myeloproliferative tumor from causing stroke,
early detection and early treatment!

To prevent myeloproliferative tumors, remind the public to remain moderately alert to common daily symptoms, and if in doubt, take a blood test to confirm. If you find that your red blood cell count is abnormally high during the usual blood test, it is recommended to check again for confirmation to prevent myeloproliferative tumors. Good and moderate prevention is more helpful for early diagnosis and early treatment!

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